PRODUCT DETAILS

About Abokit Tablet

MIFEPRISTONE+MISOPROSTOL belongs to a group of gynaecological medication called ‘Abortifacient’ used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. MIFEPRISTONE+MISOPROSTOL also works in the second trimester of the pregnancy.

MIFEPRISTONE+MISOPROSTOL contains two medicines, namely: Mifepristone and Misoprostol. Mifepristone is an anti-hormone (anti-progestogen) that acts by blocking the effects of progesterone hormone required in women to continue the pregnancy. On the other hand, Misoprostol is a prostaglandin that increases womb’s (uterus) contraction and dilates the cervix, thereby expelling the pregnancy. Thus, MIFEPRISTONE+MISOPROSTOL together cause termination of pregnancy and must be used one after the other for medical abortion.

Uses of Abokit Tablet

Medical abortion

Medicinal Benefits of Abokit Tablet

MIFEPRISTONE+MISOPROSTOL contains Mifepristone and Misoprostol. Mifepristone works by blocking the effect of progesterone (female hormone), needed to maintain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for MIFEPRISTONE+MISOPROSTOL to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete. On the other hand, second medicine is Misoprostol, that is a prostaglandin analogue, which helps in increasing the uterine contractions and relaxing the cervix. Thus Together MIFEPRISTONE+MISOPROSTOL terminates the state of pregnancy. Misoprostol should be taken at least 24-36 hours after taking mifepristone either orally or vaginally. This is a non-surgical method which is 90% successful.

Directions for Use

MIFEPRISTONE+MISOPROSTOL should be taken in dose and duration as prescribed by your doctor.

Side Effects of Abokit Tablet

Like all medicines, MIFEPRISTONE+MISOPROSTOL also has some side effects, though it is not mandatory for everyone to experience them. You may experience nausea, uterine cramps, vomiting, diarrhea, dizziness, infection following abortion, and uterine bleeding in some cases. Most of these side effects of MIFEPRISTONE+MISOPROSTOL subside with time. But if your vaginal bleeding does not, please visit the doctor immediately, and it requires immediate medical attention. 

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take MIFEPRISTONE+MISOPROSTOL, if are allergic to misoprostol and mifepristone, have heart fitted with an artificial valve, have heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking MIFEPRISTONE+MISOPROSTOL in these conditions can cause life-threatening conditions in an individual. MIFEPRISTONE+MISOPROSTOL is known to cause sleepiness, so driving or operating machinery should not be done. If you are using contraceptives devices like the intrauterine device (IUD), please remove it before taking MIFEPRISTONE+MISOPROSTOL. Regular follow up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or become unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if abortion is complete. St John’s Wort (a natural remedy used to treat mild depression) grapefruit juice should not be taken when taking MIFEPRISTONE+MISOPROSTOL as it is known to interact.

Drug Interactions

Drug-Drug Interaction:

MIFEPRISTONE+MISOPROSTOL interacts with corticosteroids (dexamethasone), antifungal (ketoconazole, itraconazole), antibiotics (erythromycin, rifampicin),  anti-epileptic (phenytoin, phenobarbital, carbamazepine), immunosuppressants (cyclosporine, tacrolimus, sirolimus), medicines to treat migraine (ergotamine). So, MIFEPRISTONE+MISOPROSTOL should not be taken along with these drugs.

Drug-Disease Interaction:

It should be taken with caution in people who have a bleeding problem, confirmed or suspected ectopic pregnancy, heart problem, liver or kidney disease, vaginal bleeding, porphyria (an inherited blood disease that may cause nervous system or skin problems).

Safety Advice

ALCOHOL

Alcohol is known to cause excessive drowsiness and if taken along with MIFEPRISTONE+MISOPROSTOL and increase uterine bleeding.

PREGNANCY

MIFEPRISTONE+MISOPROSTOL is used for medical abortion. If taken in pregnancy, it can lead to abortion.

BREAST FEEDING

MIFEPRISTONE+MISOPROSTOL should not be taken if breastfeeding as it may pass through the milk to the baby.

DRIVING

Driving is unsafe when taking MIFEPRISTONE+MISOPROSTOL as it might increase the risk of excessive bleeding.

LIVER

MIFEPRISTONE+MISOPROSTOL to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

KIDNEY

MIFEPRISTONE+MISOPROSTOL to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.